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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfa8cf3960d8ac808cde6c9607a7297357c1a2c5710b61a4a2608e019d8c2b70' 
  AND token = 'HjejkWQ01cfYIvyWFNV5wporHf6uBh+mVhIVq+WF4pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}