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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a254c236467dbd4c8fce65faf37d45c3388c887dd8e13f747f6033132c2ef4d0' 
  AND token = 'jPTlbLPe0dkGtllIGtE2lM9UmkeUv71R52jFKmvuPUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}