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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad1707cf30ff6191bd92eb000281b9c7baf3552246056a6d2296a6371590d02' 
  AND token = 'Y6DIpPsYFK3y7a/TZJY2SFzfYa0Vj4w41KC36GPFFoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}