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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a37377d0b4a6de648e14f669cb75b0274960ac601920f8726f72a73d1151dcf4' 
  AND token = 'u5qQIap7LXC0LcUG78PI4oHlK6q7fDTNQIFrNQUU2IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}