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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c04e2f50ad27cad946440fe6a591026d562208fef1ee5b65742d8c27bcc5d308' 
  AND token = 'EosOotzDYRb1T3yRM+wypP8mbrUnbuBEBPPbT4TXem8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}