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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e879083f9ef1bd8e0e895423bd2bd7ad347245c10820c7cce6e11f6d2ebf0f42' 
  AND token = 'b6AHVvW++9eXr0caP2mBMYZe4gBlrwk0gfnnKYTrxUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}