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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7ee693a01ed2d6ca69e5309b1499ff01c02649263ce2b2288f74bc8f8b496e' 
  AND token = 'hk1Poiaht+m35AYlb3O7F0NjnzdHb+WqN86BPAtbe9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}