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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97071b2644a1dce0cf24e5b3cbcce37668ce2e72876b4ec42f2c3e981e02f5aa' 
  AND token = 'bYJqPW3EVY8sA9DU5Ekr3XWJKIf1xCgQTlUe0XcF94I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}