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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c8360827aea433c7aae67a0cb054537d8e241de71e095f516ea44b0c6e5281' 
  AND token = 'Pt6fcKxO9+QFsy4xeHhyz0ERRS49N481jZ38LWJ5EEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}