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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f772d80a2af7728afc7056a3064870d314b189e416fb9f7b3adbb2c5e0004b89' 
  AND token = '6yCB4Vf+EcaxHtyRUsw6sGdko+FJ7Y2/LYpBTiG7V/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}