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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4388e90d36c0c5f8060d3dbdda89b4e6b6ba55843171374302e8c4fbd5314c72' 
  AND token = 'AXtVAEXxObUqqMFncPIzonZvWgGizSEQnOIep+YWOj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}