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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10349c9c442fb1a3aa43c1c6ae9890e72263848e509e0814bbb7005c57690446' 
  AND token = 'EZVnJvqNglciJ0bDOPW715CeCxYekjzfuh0RPN+2cYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}