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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dce0f7382663b238ee7d96ea8e4fe5776238086c3cc18e3f205894092339e07b' 
  AND token = '5znUAlicfx/raPGUrtjik8EKlBENklW5T79B2U9g7Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}