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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449c5575ffa413a90b72223cc10e2a58c79d9b9a6f0ac41cad3ffd1c89dcf5a4' 
  AND token = 'sqsLEnopb3Bialk4hm292QwCes7+Fgnwfi4T8SZLHdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}