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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be9f74db8e8521edb66d06bdf92f1b343faff95787ed9bed14917ed6bff007ef' 
  AND token = 'RcwFwY/FCAyC1Aa4XdhRqfK+F+Ajm6aWHy6RkgkdrI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}