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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b02e0f2918fc2d2beb5ff39d05ea800be64b544957a3b2256f851a63b388e10e' 
  AND token = 'PMXIwlAR0kuZ8O5oOG9sCUG+cXO3xHDSy7V00AaRmvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}