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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf73cc9003ce8fcc524537b96d1821095ea9c95cb1cf24ea47f4ea72ec80e777' 
  AND token = '9+SZgSi9bqGDGFaDK8+mnz/9MTtVY4W98GOS5jC/7Eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}