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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '967d9f25a76e72e675529efd4cc57b66c3f811cabe99b04b0db34ae8b377e03d' 
  AND token = 'MXqplUWUYcalxT4n/OYoWBTLdNkOawYznrDbfyw1N3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}