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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77302bd842a672f0a62f4580a072900c337e03151619ce9af7fbd777f1ec76a8' 
  AND token = 'CrSaMRau52dlp6n+N3lXO17SAwTLasnNhxnxIMbnpqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}