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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb2461869ca0f07f9f24f4f0156a9cf02d76135b6269413809dc726cb1f1dfb5' 
  AND token = 'QoPx/VNnKPL9ziMS/IAkgpvsnkhWDUdKFQ5tadQcDw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}