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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d16264a705d8f1a75c74e5024bfaf8708097c28affd58441a19dcf0a628fa4c' 
  AND token = 'LfKgbX854f6HzvVZtnNYhST/rPvpOyViehxS2FCK46A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}