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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61ddec884097e1cdb47fcf1ef2ea74b3280aee8abdc45447d3ead519c4ad9008' 
  AND token = 'Xm+Q1HaA19vefoKXUk0vYLNq4S7T8Uaw5UjHe53+9wU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}