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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0a15f8a0d24c2658ddd7b4a55561112b09fe5d29b0629622a8851fa517e962' 
  AND token = 'cYCY4pzvQHg9228OZ2hINn/E+tgEBtqjh8NsGWEtC9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}