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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea4fd8808d54c1f3eeae88bf45a61d850621eda20e969f128e00b9b7d819e2e' 
  AND token = 'AxI5vSYRtZBfGB3SexHHPc3fDEwLBa7X4Av3Ms5LSGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}