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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e9d2a7de34b60e801846be601ba1c78474d0f5df0c7a46f031d2b11afd7c37b' 
  AND token = 't2E2O12zRR6snzNAd1XOmaNvHuFyBlG+0QwMr2v01/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}