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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3f6a35ec6eca3c9c5247ea3038df94a4413a9edb6e7c62611a6e54695ee599' 
  AND token = 'o+5S1moKgnnIFVUL2c1kPV3QQt0uaWkRBhVHlx/6fO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}