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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a56a690f535ddf0700825508ba0effe9941c3b03b6fe21761a36ff9bbe7565d4' 
  AND token = 'JkG6JRTntH/8pekpKrtA7OKrJD4Kgs4zuvcp2CQw7mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}