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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a34865cc2c423ef6e791d496e35dad59e145cd85738c86e6d7fc18fdff47594e' 
  AND token = 'TgKdASf3bv0Dg6YGFEOt2DzvofxJ9t7x2YkBlqo5IoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}