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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ec91a423afa112ed08448f9b2896388b0899109331019f37e9319092a3202be' 
  AND token = 'uPoQ8MNr3cVrqiXaEY70pXichlfV00UbxeuVrUBXjYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}