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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b284cf9622d7788a997bb75838fb4edae1c4ccab7033c31b1fb40a1925bd646' 
  AND token = 'vDWHhXsAETXrEzmh3w7MqTrZ7bQ7xQTold74kw2wPbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}