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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0f55973c56d0221c7a9dcfa43d17556a103ed65ecc1b78018051ee3d8bd05da' 
  AND token = 'L8epSjyMuPvJRxy0xkaPZcKkylNJ1JAJd2V+H5IMIkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}