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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a1abdf9b97d51c6fdf5bde6289212608a372e7d0f1d3ec4a932a890dcc37c5b' 
  AND token = '/osk+tmN8x6hYGCFNph1TsgnIfcBkmdcoNQP8zPhvbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}