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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f4428bcfa80e6f8fc2daee6a9577c080a7a497d7f353441d59d5642309765e3' 
  AND token = 'LzVS70eVmh8qPpi2XN0zV0xnkri1c3PdRhQT1xA/R4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}