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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75323f3e51a9b86d6a3fa71bec2eeaa041099e1494ecd6aefd21d30544fb4cb4' 
  AND token = 'V8vKUc5OnxmRge0GprT9esDjy4UDToY/pK8uZb6niXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}