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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e716bf1b2f19581aada11f4fd4199ad1b410dac00a07e43acc42b0384aff95d7' 
  AND token = 'ZC8nQZUZbK2g72uEu6THphePypSSLCXKPhZq5SljUKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}