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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1848339dc94e8858e1ac50a632245e38a690ca84d3179aa65104f1a743147320' 
  AND token = '8UEM5lEI+vNfpiPzmKb1xdr6CHVVfrQ68OyQMM4R5uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}