SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c8ccdf5775d606fe1fa698033459ef7c772ef0425de1cae94ca82c67e7ae92' 
  AND token = 'icAQGUaG2i+WGhRSeUindm5cSks/pZtPudQP2qd9G0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}