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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'daca110b1487dbfe90237e0d0f59893da1bfa039c6c527be2059022f5a671629' 
  AND token = 'FZHuLEXQ6B/cc+guv7j1l2UR5i06o/NIqyBM9W5MDbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}