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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c94abdd2c956097f5ea542c605379015640a0b535e1f70b1aaec0bcf3984b4' 
  AND token = 'Vj3C7q+OIxXNL2ztgAQAcFfM+82tQf6n1IWZy7cF51s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}