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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05bac2c7a2500975c9d11c3c93f128afc7907189a984666e6c50d3e4fed9c49' 
  AND token = 'blR9BjDb5iWFCLmC+27bpEPeuK/x7A57yOigmaclZZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}