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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99f02781ed544eb9ccaa59e913029773c4471320e77db1bf82190b40e0595089' 
  AND token = 'bfQKNgV5N8sDbg5Pxi3Q8E4oLnh4kHN8juKgq/oOlwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}