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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e4e091d72c964d1bf3b3736b193fa378708ec44587e96f26ccc1fac0bacd59' 
  AND token = 'peTE1A/+XK/qvbyR62lJ3gO3aXaBVIM5pYXbfWKr3gI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}