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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b928c2b313d4d59b07c47219b29d7fbc1a0b8fe666af2b142d20595e5d67425' 
  AND token = 'wyg2LRYcHL21aXd4v8gtllftBlI5K40fXOTzSPkZxO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}