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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29b49c8c193de2b48a246b77a46a827114564f3abbbe413bc98be5ad5bdf2a4c' 
  AND token = 'k+AHc9q9h2R3o6yUHQK6FL5aw+g/EZ1fx6FpbyciEBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}