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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a951274453cbf9ed61a032ef9288b0c4f49d7ac85d165af8ae08ae93ab7fe4' 
  AND token = 'WBAn9NQ8qppFAIdwiR/DdamhNevlhwHw+E1Vh/bdXiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}