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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be0b253510ea56f1bfa48fb06f53f102b4c41c545270af41ab021a9fab2f9db1' 
  AND token = '+W4Yi2IsN7CKzdiFVB4gzD2wN22lKUJ5+EFMT/lKbiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}