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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b627a64f67ea721e6b76de263ee70156e0eda68c4dd460388d53540022bd9b1c' 
  AND token = 'pttgn2swjvuXgAV7ZtBB886cp2Fuz1f0DOAoDvRSeng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}