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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4a126d359a6c5cdf42e2e4223487c98b5db1629112a8ad760d01990cce0dae5' 
  AND token = '3VA0LxG0fpUfIbNGgwdFKQpH0vz7HNUn4n7+MwFJBBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}