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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0abb33873270be5cf03fb8118b441c75a9fe65d0eee475b0ed30df5a54351740' 
  AND token = 'RZ2Lwyy3Af9n3svAqUCc7y58rQHRTo6N8JvoeOrG3pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}