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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5669a0164269965605b7015ac1c429b7e1ac7a15c599dc6278c397de1803f6c' 
  AND token = 'JKdO2JJ0abam/XEETpXxiDIF3JW0smtlMeiNHyi9Qw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}